ARFGAP3 M431I

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Mutation:

Summary

Isoform:

NM_014570

Position:

431

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

[0.0199681]

PTM Site: 425K

Affected site:

Position: 425

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431T	QKKFGNVKAISSD[M/T]MY	6	distal
431I	QKKFGNVKAISSD[M/I]MY	6	distal
420T	QK[K/T]KFGNVKAISSDMY	5	distal
421C	QKK[F/C]FGNVKAISSDMY	4	distal

PTM Site: 428S

Affected site:

Position: 428

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431T	FGNVKAISSD[M/T]MYFGR	3	distal
431I	FGNVKAISSD[M/I]MYFGR	3	distal

PTM Site: 429S

Affected site:

Position: 429

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431T	GNVKAISSD[M/T]MYFGRQ	2	proximal
431I	GNVKAISSD[M/I]MYFGRQ	2	proximal

PTM Site: 432Y

Affected site:

Position: 432

Residue: Y

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431T	KAISSD[M/T]MYFGRQSQA	1	proximal
431I	KAISSD[M/I]MYFGRQSQA	1	proximal

PTM Site: 437S

Affected site:

Position: 437

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431T	D[M/T]MYFGRQSQADYETR	6	distal
431I	D[M/I]MYFGRQSQADYETR	6	distal
442D	DMYFGRQSQADY[E/D]ETR	5	distal
441H	DMYFGRQSQAD[Y/H]YETR	4	distal

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