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Mutation:
CYLD S398A
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.05]
Minor Allele Frequency: (1000 Genomes)
[0.059904200000000005]
PTM Site: 393T
Affected site:
Position: 393
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 389R | KSL[T/R]TEISTDFDRSSP | 4 |
distal
|
| 391T | KSLTE[I/T]ISTDFDRSSP | 2 |
proximal
|
| 397C | KSLTEISTDFD[R/C]RSSP | 4 |
distal
|
| 397H | KSLTEISTDFD[R/H]RSSP | 4 |
distal
|
| 398A | KSLTEISTDFDR[S/A]SSP | 5 |
distal
|
| 393A | KSLTEIS[T/A]TDFDRSSP | 0 |
direct
|
| 390V | KSLT[E/V]EISTDFDRSSP | 3 |
distal
|
| 388F | KS[L/F]LTEISTDFDRSSP | 5 |
distal
|
| 393I | KSLTEIS[T/I]TDFDRSSP | 0 |
direct
|
PTM Site: 399S
Affected site:
Position: 399
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 397C | STDFD[R/C]RSSPPLQPPP | 2 |
network-rewiring
|
| 397H | STDFD[R/H]RSSPPLQPPP | 2 |
network-rewiring
|
| 398A | STDFDR[S/A]SSPPLQPPP | 1 |
proximal
|
| 393A | S[T/A]TDFDRSSPPLQPPP | 6 |
distal
|
| 393I | S[T/I]TDFDRSSPPLQPPP | 6 |
distal
|
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