GMIP T446M

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Mutation:

Summary

Isoform:

NM_016573

Position:

446

Ref:

Mutation:

PTM impact:

distal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0154]

Minor Allele Frequency: (1000 Genomes)

[0.0199681]

PTM Site: 439T

Affected site:

Position: 439

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
433W	S[R/W]RSLDSPTSSPGAGT	6	distal
436N	SRSL[D/N]DSPTSSPGAGT	3	distal
437A	SRSLD[S/A]SPTSSPGAGT	2	proximal
440F	SRSLDSPT[S/F]SSPGAGT	1	proximal

PTM Site: 440S

Affected site:

Position: 440

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
446M	RSLDSPTSSPGAG[T/M]TR	6	distal
436N	RSL[D/N]DSPTSSPGAGTR	4	distal
437A	RSLD[S/A]SPTSSPGAGTR	3	distal
440F	RSLDSPT[S/F]SSPGAGTR	0	direct

PTM Site: 441S

Affected site:

Position: 441

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
446M	SLDSPTSSPGAG[T/M]TRQ	5	distal
436N	SL[D/N]DSPTSSPGAGTRQ	5	distal
437A	SLD[S/A]SPTSSPGAGTRQ	4	distal
440F	SLDSPT[S/F]SSPGAGTRQ	1	proximal

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