You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
PPP1R12C A511V
Summary
Isoform:
Position:
511
Ref:
A
Mutation:
V
PTM impact:
proximal
PTM affected:
1
Kinases:
CDK2
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 509S
Affected site:
Position: 509
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 514D | SRIPEPESPAKP[N/D]NVP | 5 |
distal
|
| 511V | SRIPEPESP[A/V]AKPNVP | 2 |
proximal
|
| 506D | SRIP[E/D]EPESPAKPNVP | 3 |
distal
|
| 505R | SRI[P/R]PEPESPAKPNVP | 4 |
distal
|
| 505S | SRI[P/S]PEPESPAKPNVP | 4 |
distal
|
| 505L | SRI[P/L]PEPESPAKPNVP | 4 |
distal
|
| 505A | SRI[P/A]PEPESPAKPNVP | 4 |
distal
|
| 507L | SRIPE[P/L]PESPAKPNVP | 2 |
proximal
|
If you have any questions or feedback about this mutation:
Contact us