You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
PML P413L
Summary
Isoform:
Position:
413
Ref:
P
Mutation:
L
PTM impact:
distal
PTM affected:
2
Kinases:
MAPK7
Clinical Information
Cancer types: (TCGA MC3)
STAD
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 408S
Affected site:
Position: 408
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 403N | KA[S/N]SPEAASTPRDPID | 5 |
distal
|
| 413L | KASPEAASTPRD[P/L]PID | 5 |
distal
|
| 410S | KASPEAAST[P/S]PRDPID | 2 |
proximal
|
| 407S | KASPEA[A/S]ASTPRDPID | 1 |
proximal
|
PTM Site: 409T
Affected site:
Position: 409
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 403N | A[S/N]SPEAASTPRDPIDV | 6 |
distal
|
| 413L | ASPEAASTPRD[P/L]PIDV | 4 |
distal
|
| 410S | ASPEAAST[P/S]PRDPIDV | 1 |
network-rewiring
|
| 407S | ASPEA[A/S]ASTPRDPIDV | 2 |
proximal
|
If you have any questions or feedback about this mutation:
Contact us