ANXA11 I278V

You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

Mutation:

Summary

Isoform:

NM_145869

Position:

278

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.3767]

Minor Allele Frequency: (1000 Genomes)

[0.239617]

PTM Site: 271K

Affected site:

Position: 271

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
268V	KTIL[A/V]ALMKTPVLFDI	3	distal
276V	KTILALMKTPVL[F/V]FDI	5	distal

PTM Site: 279Y

Affected site:

Position: 279

Residue: Y

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
281T	TPVLFDIYE[I/T]IKEAIK	2	proximal
278V	TPVLFD[I/V]IYEIKEAIK	1	proximal
276V	TPVL[F/V]FDIYEIKEAIK	3	distal

PTM Site: 282K

Affected site:

Position: 282

Residue: K

Type: sumoylation, acetylation, ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
288I	LFDIYEIKEAIKG[V/I]VG	6	distal
281T	LFDIYE[I/T]IKEAIKGVG	1	proximal
278V	LFD[I/V]IYEIKEAIKGVG	4	distal
276V	L[F/V]FDIYEIKEAIKGVG	6	distal

If you have any questions or feedback about this mutation: