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Summary

Isoform:
Position:
281
Ref:
I
Mutation:
T
PTM impact:
proximal
PTM affected:
3
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0461]

Minor Allele Frequency: (1000 Genomes)

[0.059904200000000005]

PTM Site: 279Y

Affected site:

Position: 279
Residue: Y
Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation In sequence Distance Impact
281T TPVLFDIYE[I/T]IKEAIK 2
proximal
278V TPVLFD[I/V]IYEIKEAIK 1
proximal
276V TPVL[F/V]FDIYEIKEAIK 3
distal

PTM Site: 282K

Affected site:

Position: 282
Residue: K
Type: sumoylation, acetylation, ubiquitination

Impact:

proximal

Other known mutations affecting this site

Mutation In sequence Distance Impact
288I LFDIYEIKEAIKG[V/I]VG 6
distal
281T LFDIYE[I/T]IKEAIKGVG 1
proximal
278V LFD[I/V]IYEIKEAIKGVG 4
distal
276V L[F/V]FDIYEIKEAIKGVG 6
distal

PTM Site: 286K

Affected site:

Position: 286
Residue: K
Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
288I YEIKEAIKG[V/I]VGTDEA 2
proximal
281T YE[I/T]IKEAIKGVGTDEA 5
distal

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