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Mutation:
NFATC1 R260L
Summary
Isoform:
Position:
260
Ref:
R
Mutation:
L
PTM impact:
distal
PTM affected:
2
Kinases:
PKA group,
PRKACA,
PRKCA,
PIM1,
DYRK1A,
PIM1
Clinical Information
Cancer types: (TCGA MC3)
BLCA
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 256S
Affected site:
Position: 256
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 262Q | PCNKRKYSLNGRQ[P/Q]PP | 6 |
distal
|
| 260L | PCNKRKYSLNG[R/L]RQPP | 4 |
distal
|
PTM Site: 265S
Affected site:
Position: 265
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 262Q | NGRQ[P/Q]PPYSPHHSPTP | 3 |
distal
|
| 263A | NGRQP[P/A]PYSPHHSPTP | 2 |
proximal
|
| 268D | NGRQPPYSPH[H/D]HSPTP | 3 |
distal
|
| 267Y | NGRQPPYSP[H/Y]HHSPTP | 2 |
proximal
|
| 260L | NG[R/L]RQPPYSPHHSPTP | 5 |
distal
|
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