You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
EIF4G1 L741F
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 736K
Affected site:
Position: 736
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 741F | RRSLGNIKFIGE[L/F]LFK | 5 |
distal
|
| 733E | RRSL[G/E]GNIKFIGELFK | 3 |
distal
|
| 730C | R[R/C]RSLGNIKFIGELFK | 6 |
distal
|
PTM Site: 743K
Affected site:
Position: 743
Residue: K
Type: ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 741F | KFIGE[L/F]LFKLKMLTEA | 2 |
proximal
|
If you have any questions or feedback about this mutation:
Contact us