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Mutation:
EGFR N234S
Summary
Isoform:
Position:
234
Ref:
N
Mutation:
S
PTM impact:
distal
PTM affected:
1
Kinases:
AKT1,
AKT2
Clinical Information
Cancer types: (TCGA MC3)
SKCM
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 229S
Affected site:
Position: 229
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 224C | RC[R/C]RGKSPSDCCHNQC | 5 |
network-rewiring
|
| 224H | RC[R/H]RGKSPSDCCHNQC | 5 |
network-rewiring
|
| 229C | RCRGKSP[S/C]SDCCHNQC | 0 |
direct
|
| 223Y | R[C/Y]CRGKSPSDCCHNQC | 6 |
distal
|
| 234S | RCRGKSPSDCCH[N/S]NQC | 5 |
distal
|
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