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BCLAF1 (NM_001077441) - BCL2 associated transcription factor 1

Bcl-2-Associated Transcription Factor 1 Isoform 3

PTM Interaction Network Visualisation

Protein summary

This is an alternative isoform of BCLAF1 protein. View all 4 isoforms
BCLAF1: bcl-2-associated transcription factor 1 isoform 3
Description:

This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Strand
-
Chromosome
6
Protein
747 residues
All mutations
258
PTM sites
131
CDS
136,582,247 - 136,601,004
Transcription
136,578,000 - 136,610,989
78.18% of sequence is predicted to be disordered

Usage summary

Network

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PTM site

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Kinases group

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Kinase, PTM site or protein

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External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 9774
UniProt
Ensembl