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BCLAF1 (NM_001077441) - BCL2 associated transcription factor 1
Bcl-2-Associated Transcription Factor 1 Isoform 3
Legend
Mutation impacts
direct
network-rewiring
motif-changing
proximal
distal
none
Sites
multiple types
acetylation
methylation
succinylation
sumoylation
ubiquitination
glycosylation
- C-linked
- N-linked
- O-linked
- S-linked
phosphorylation
- SARS-CoV-2
Others
Exact position of a PTM site
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Mutations Visualisation
Protein summary
This is an alternative isoform of BCLAF1 protein.
View all 4 isoforms
BCLAF1:
bcl-2-associated transcription factor 1 isoform 3
Description:
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- Strand
- -
- Chromosome
- 6
- Protein
- 747 residues
- All mutations
- 258
- PTM sites
- 131
- CDS
- 136,582,247 - 136,601,004
- Transcription
- 136,578,000 - 136,610,989
External references
Mappings retrieved from NCBI & UniProt.