TOPBP1 (NM_007027) - topoisomerase (DNA) II binding protein 1
Dna Topoisomerase 2-Binding Protein 1
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This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008].
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Transcript exon combination :: BC151237.1, SRR1660803.23079.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350]
- 1522 residues
- All mutations
- PTM sites
- 133,320,093 - 133,379,971
- 133,319,448 - 133,380,737
- gene: 11073