ATRIP (NM_130384) - ATR interacting protein

Atr-Interacting Protein Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of ATRIP protein. View all 4 isoforms
ATRIP: ATR-interacting protein isoform 1
Description:

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012].

Strand
+
Chromosome
3
Protein
791 residues
All mutations
117
PTM sites
19
CDS
48,488,249 - 48,506,953
Transcription
48,488,113 - 48,507,054
45.13% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 84126
Uniprot
Ensembl