After several years of serving the research community, our ActiveDriverDB database will be retired on May 1st 2026. Please make sure to download any data you need and update your links or workflows before that date.

We want to sincerely thank all our users for their support, feedback, and collaboration over the years — your contributions have been invaluable to this project. A special thank you to Dr. Michal Krassowski for leading the development of our open-source software and database.

For any questions or assistance, please contact Jüri Reimand (juri.reimand@utoronto.ca).

You are viewing an older version (2020) of the ActiveDriverDB. To view the current (2021) version please visit activedriverdb.org

Download

 

Download input files of the ActiveDriver method

 

Download entire datasets as ZIP files

  1. All cancer mutations affecting PTM sites*
  2. All disease mutations affecting PTM sites*
  3. All population variants affecting PTM sites*
  4. Site-specific network of kinases and targets*

 Or alternatively, download all the data* at once.

 

Download datasets with genomic coordinates

  1. All cancer mutations affecting PTM sites*
  2. All disease mutations affecting PTM sites*
  3. Population variants affecting PTM sites (ESP6500)*
  4. Population variants affecting PTM sites (1000 Genomes)*

 

The download data (especially those marked with *) are partially based on PhosphositePlus data and are not for commercial use.

Please see Terms and Conditions of PSP on the following page: Terms of Use and License.

 

This website was most recently updated on 15th March 2020.

For the data from the previous v2017 version, please visit: activedriverdb.org/v2017/download/

 

Download source code

The source code can be downloaded from the GitHub repository: github.com/reimandlab/ActiveDriverDB.

Use one of the following commands to download it quickly:

git clone https://github.com/reimandlab/ActiveDriverDB.git
wget https://github.com/reimandlab/ActiveDriverDB/archive/master.zip

Please, see README.md file for installation and deployment instructions. The database structure can be generated using source files linked above.