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Mutation:

TP53 E343Q

Summary

Isoform:
NM_000546
Position:
343
Ref:
E
Mutation:
Q
PTM impact:
distal
PTM affected:
1
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0077]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 337R

Affected site:

Position: 337
Residue: R
Type: methylation

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
342P LQIRGRERFEMF[R/P]REL 5
distal
342Q LQIRGRERFEMF[R/Q]REL 5
distal
340K LQIRGRERFE[M/K]MFREL 3
distal
339V LQIRGRERF[E/V]EMFREL 2
proximal
339G LQIRGRERF[E/G]EMFREL 2
proximal
339Q LQIRGRERF[E/Q]EMFREL 2
proximal
339K LQIRGRERF[E/K]EMFREL 2
proximal
338L LQIRGRER[F/L]FEMFREL 1
proximal
338C LQIRGRER[F/C]FEMFREL 1
proximal
337L LQIRGRE[R/L]RFEMFREL 0
direct
337P LQIRGRE[R/P]RFEMFREL 0
direct
337H LQIRGRE[R/H]RFEMFREL 0
direct
337C LQIRGRE[R/C]RFEMFREL 0
direct
337G LQIRGRE[R/G]RFEMFREL 0
direct
335P LQIRG[R/P]RERFEMFREL 2
proximal
335H LQIRG[R/H]RERFEMFREL 2
proximal
335C LQIRG[R/C]RERFEMFREL 2
proximal
334E LQIR[G/E]GRERFEMFREL 3
distal
334W LQIR[G/W]GRERFEMFREL 3
distal
334R LQIR[G/R]GRERFEMFREL 3
distal
333H LQI[R/H]RGRERFEMFREL 4
distal
333C LQI[R/C]RGRERFEMFREL 4
distal
332M LQ[I/M]IRGRERFEMFREL 5
distal
331R L[Q/R]QIRGRERFEMFREL 6
distal
331K L[Q/K]QIRGRERFEMFREL 6
distal
343Q LQIRGRERFEMFR[E/Q]EL 6
distal
334V LQIR[G/V]GRERFEMFREL 3
distal
331H L[Q/H]QIRGRERFEMFREL 6
distal
341L LQIRGRERFEM[F/L]FREL 4
distal
341V LQIRGRERFEM[F/V]FREL 4
distal
337S LQIRGRE[R/S]RFEMFREL 0
direct
338I LQIRGRER[F/I]FEMFREL 1
proximal
332F LQ[I/F]IRGRERFEMFREL 5
distal

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