TRA2B R119L

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Mutation:

Summary

Isoform:

NM_001243879

Position:

119

Ref:

Mutation:

PTM impact:

distal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

LUSC

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 112T

Affected site:

Position: 112

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
108I	GIY[M/I]MGRPTYGSSRRR	4	distal
117S	GIYMGRPTYGSS[R/S]RRR	5	distal
117L	GIYMGRPTYGSS[R/L]RRR	5	distal

PTM Site: 115S

Affected site:

Position: 115

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
119L	MGRPTYGSSRR[R/L]RDYY	4	distal
117S	MGRPTYGSS[R/S]RRRDYY	2	network-rewiring
117L	MGRPTYGSS[R/L]RRRDYY	2	network-rewiring

PTM Site: 116S

Affected site:

Position: 116

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
119L	GRPTYGSSRR[R/L]RDYYD	3	distal
117S	GRPTYGSS[R/S]RRRDYYD	1	proximal
117L	GRPTYGSS[R/L]RRRDYYD	1	proximal

PTM Site: 124R

Affected site:

Position: 124

Residue: R

Type: methylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
119L	RR[R/L]RDYYDRGYDRGYD	5	distal
128W	RRRDYYDRGYD[R/W]RGYD	4	distal

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