TRA2B Y168N

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Mutation:

Summary

Isoform:

NM_001243879

Position:

168

Ref:

Mutation:

PTM impact:

direct

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

Breast-AdenoCa

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 164S

Affected site:

Position: 164

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
167T	DQIYRRRSPS[P/T]PYYSR	3	distal
158E	D[Q/E]QIYRRRSPSPYYSR	6	distal
167A	DQIYRRRSPS[P/A]PYYSR	3	distal
168N	DQIYRRRSPSP[Y/N]YYSR	4	distal

PTM Site: 166S

Affected site:

Position: 166

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
167T	IYRRRSPS[P/T]PYYSRGG	1	network-rewiring
171H	IYRRRSPSPYYS[R/H]RGG	5	distal
167A	IYRRRSPS[P/A]PYYSRGG	1	network-rewiring
168N	IYRRRSPSP[Y/N]YYSRGG	2	proximal

PTM Site: 168Y

Affected site:

Position: 168

Residue: Y

Type: phosphorylation

Impact:

direct

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
167T	RRRSPS[P/T]PYYSRGGYR	1	proximal
171H	RRRSPSPYYS[R/H]RGGYR	3	distal
167A	RRRSPS[P/A]PYYSRGGYR	1	proximal
168N	RRRSPSP[Y/N]YYSRGGYR	0	direct

PTM Site: 169Y

Affected site:

Position: 169

Residue: Y

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
167T	RRSPS[P/T]PYYSRGGYRS	2	proximal
171H	RRSPSPYYS[R/H]RGGYRS	2	proximal
167A	RRSPS[P/A]PYYSRGGYRS	2	proximal
168N	RRSPSP[Y/N]YYSRGGYRS	1	proximal

PTM Site: 170S

Affected site:

Position: 170

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
167T	RSPS[P/T]PYYSRGGYRSR	3	distal
171H	RSPSPYYS[R/H]RGGYRSR	1	proximal
167A	RSPS[P/A]PYYSRGGYRSR	3	distal
168N	RSPSP[Y/N]YYSRGGYRSR	2	proximal

PTM Site: 171R

Affected site:

Position: 171

Residue: R

Type: methylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
167T	SPS[P/T]PYYSRGGYRSRS	4	distal
171H	SPSPYYS[R/H]RGGYRSRS	0	direct
177L	SPSPYYSRGGYRS[R/L]RS	6	distal
167A	SPS[P/A]PYYSRGGYRSRS	4	distal
168N	SPSP[Y/N]YYSRGGYRSRS	3	distal

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