SORBS2 S380L

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Mutation:

Summary

Isoform:

NM_003603

Position:

380

Ref:

Mutation:

PTM impact:

direct

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

BLCA

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 380S

Affected site:

Position: 380

Residue: S

Type: phosphorylation

Impact:

direct

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
374Q	G[R/Q]RVDLPGSSTTLTKS	6	distal
380L	GRVDLPG[S/L]SSTTLTKS	0	direct
379E	GRVDLP[G/E]GSSTTLTKS	1	proximal

PTM Site: 381S

Affected site:

Position: 381

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
380L	RVDLPG[S/L]SSTTLTKSF	1	proximal
379E	RVDLP[G/E]GSSTTLTKSF	2	network-rewiring

PTM Site: 385T

Affected site:

Position: 385

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
380L	PG[S/L]SSTTLTKSFTSSS	5	distal
379E	P[G/E]GSSTTLTKSFTSSS	6	distal

PTM Site: 387S

Affected site:

Position: 387

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact

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