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Mutation:
FMNL1 L692F
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0154]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 685S
Affected site:
Position: 685
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 682R | EEQF[K/R]KTKSQGPSLDL | 3 |
network-rewiring
|
| 681L | EEQ[F/L]FKTKSQGPSLDL | 4 |
distal
|
PTM Site: 689S
Affected site:
Position: 689
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 692F | KTKSQGPSLD[L/F]LSALK | 3 |
distal
|
| 694T | KTKSQGPSLDLS[A/T]ALK | 5 |
distal
|
PTM Site: 693S
Affected site:
Position: 693
Residue: S
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 692F | QGPSLD[L/F]LSALKSKAA | 1 |
proximal
|
| 694T | QGPSLDLS[A/T]ALKSKAA | 1 |
proximal
|
PTM Site: 696K
Affected site:
Position: 696
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 692F | SLD[L/F]LSALKSKAAQKA | 4 |
distal
|
| 694T | SLDLS[A/T]ALKSKAAQKA | 2 |
proximal
|
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