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Mutation:
G2E3 D334H
Summary
Clinical Information
Cancer types: (TCGA MC3)
STAD
Cancer types: (PCAWG)
Stomach-AdenoCA
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 327S
Affected site:
Position: 327
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 321T | S[P/T]PKLPRQSPGSQSKD | 6 |
distal
|
| 321L | S[P/L]PKLPRQSPGSQSKD | 6 |
distal
|
| 322E | SP[K/E]KLPRQSPGSQSKD | 5 |
distal
|
| 328L | SPKLPRQS[P/L]PGSQSKD | 1 |
network-rewiring
|
| 326L | SPKLPR[Q/L]QSPGSQSKD | 1 |
proximal
|
PTM Site: 333K
Affected site:
Position: 333
Residue: K
Type: ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 328L | QS[P/L]PGSQSKDLLRQGS | 5 |
distal
|
| 334H | QSPGSQSK[D/H]DLLRQGS | 1 |
proximal
|
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