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Mutation:
UBE2O T510M
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 514K
Affected site:
Position: 514
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 512H | GSGTS[R/H]RKKSIPLSIK | 2 |
proximal
|
| 510M | GSG[T/M]TSRKKSIPLSIK | 4 |
distal
|
| 517T | GSGTSRKKSI[P/T]PLSIK | 3 |
distal
|
PTM Site: 515S
Affected site:
Position: 515
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 512H | SGTS[R/H]RKKSIPLSIKN | 3 |
network-rewiring
|
| 510M | SG[T/M]TSRKKSIPLSIKN | 5 |
distal
|
| 517T | SGTSRKKSI[P/T]PLSIKN | 2 |
proximal
|
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