UBE2O P517T

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Mutation:

Summary

Isoform:

NM_022066

Position:

517

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

UCEC

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 514K

Affected site:

Position: 514

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
512H	GSGTS[R/H]RKKSIPLSIK	2	proximal
510M	GSG[T/M]TSRKKSIPLSIK	4	distal
517T	GSGTSRKKSI[P/T]PLSIK	3	distal

PTM Site: 515S

Affected site:

Position: 515

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
512H	SGTS[R/H]RKKSIPLSIKN	3	network-rewiring
510M	SG[T/M]TSRKKSIPLSIKN	5	distal
517T	SGTSRKKSI[P/T]PLSIKN	2	proximal

PTM Site: 519S

Affected site:

Position: 519

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
517T	RKKSI[P/T]PLSIKNLKRK	2	proximal

PTM Site: 521K

Affected site:

Position: 521

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
517T	KSI[P/T]PLSIKNLKRKHK	4	distal

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