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Mutation:
MAP2K5 H118R
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 121K
Affected site:
Position: 121
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 125Q | ERNIHGLKVNT[R/Q]RAGP | 4 |
distal
|
| 115W | E[R/W]RNIHGLKVNTRAGP | 6 |
distal
|
| 118R | ERNI[H/R]HGLKVNTRAGP | 3 |
distal
|
| 126S | ERNIHGLKVNTR[A/S]AGP | 5 |
distal
|
| 127V | ERNIHGLKVNTRA[G/V]GP | 6 |
distal
|
PTM Site: 125R
Affected site:
Position: 125
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 125Q | HGLKVNT[R/Q]RAGPSQHS | 0 |
direct
|
| 128S | HGLKVNTRAG[P/S]PSQHS | 3 |
distal
|
| 131Y | HGLKVNTRAGPSQ[H/Y]HS | 6 |
distal
|
| 126S | HGLKVNTR[A/S]AGPSQHS | 1 |
proximal
|
| 127V | HGLKVNTRA[G/V]GPSQHS | 2 |
proximal
|
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