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Mutation:
NFATC1 S273P
Summary
Clinical Information
Cancer types: (TCGA MC3)
LUSC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 269S
Affected site:
Position: 269
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 274L | PPYSPHHSPTPS[P/L]PHG | 5 |
distal
|
| 273P | PPYSPHHSPTP[S/P]SPHG | 4 |
distal
|
| 263A | P[P/A]PYSPHHSPTPSPHG | 6 |
distal
|
| 268D | PPYSPH[H/D]HSPTPSPHG | 1 |
proximal
|
| 267Y | PPYSP[H/Y]HHSPTPSPHG | 2 |
proximal
|
PTM Site: 277S
Affected site:
Position: 277
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 274L | PTPS[P/L]PHGSPRVSVTD | 3 |
distal
|
| 281T | PTPSPHGSPRV[S/T]SVTD | 4 |
distal
|
| 282M | PTPSPHGSPRVS[V/M]VTD | 5 |
distal
|
| 273P | PTP[S/P]SPHGSPRVSVTD | 4 |
distal
|
| 276S | PTPSPH[G/S]GSPRVSVTD | 1 |
proximal
|
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