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Mutation:
PKMYT1 R134Q
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 139K
Affected site:
Position: 139
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 142R | DGRLYAVKRS[M/R]MSPFR | 3 |
distal
|
| 140C | DGRLYAVK[R/C]RSMSPFR | 1 |
proximal
|
| 134Q | DG[R/Q]RLYAVKRSMSPFR | 5 |
distal
|
| 133S | D[G/S]GRLYAVKRSMSPFR | 6 |
distal
|
PTM Site: 141S
Affected site:
Position: 141
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 142R | RLYAVKRS[M/R]MSPFRGP | 1 |
proximal
|
| 146Q | RLYAVKRSMSPF[R/Q]RGP | 5 |
distal
|
| 140C | RLYAVK[R/C]RSMSPFRGP | 1 |
proximal
|
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