GMIP V426M

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Mutation:

Summary

Isoform:

NM_016573

Position:

426

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0077]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 421S

Affected site:

Position: 421

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
426M	TPGPTPGSDVDS[V/M]VGG	5	distal
419L	TPGPT[P/L]PGSDVDSVGG	2	proximal

PTM Site: 425S

Affected site:

Position: 425

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431Q	TPGSDVDSVGGGS[E/Q]ES	6	distal
426M	TPGSDVDS[V/M]VGGGSES	1	proximal
419L	T[P/L]PGSDVDSVGGGSES	6	distal
429C	TPGSDVDSVGG[G/C]GSES	4	distal

PTM Site: 430S

Affected site:

Position: 430

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
433W	VDSVGGGSES[R/W]RSLDS	3	distal
432C	VDSVGGGSE[S/C]SRSLDS	2	proximal
431Q	VDSVGGGS[E/Q]ESRSLDS	1	proximal
426M	VDS[V/M]VGGGSESRSLDS	4	distal
436N	VDSVGGGSESRSL[D/N]DS	6	distal
429C	VDSVGG[G/C]GSESRSLDS	1	proximal

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