GMIP E431Q

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Mutation:

Summary

Isoform:

NM_016573

Position:

431

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0077]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 425S

Affected site:

Position: 425

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
431Q	TPGSDVDSVGGGS[E/Q]ES	6	distal
426M	TPGSDVDS[V/M]VGGGSES	1	proximal
419L	T[P/L]PGSDVDSVGGGSES	6	distal
429C	TPGSDVDSVGG[G/C]GSES	4	distal

PTM Site: 430S

Affected site:

Position: 430

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
433W	VDSVGGGSES[R/W]RSLDS	3	distal
432C	VDSVGGGSE[S/C]SRSLDS	2	proximal
431Q	VDSVGGGS[E/Q]ESRSLDS	1	proximal
426M	VDS[V/M]VGGGSESRSLDS	4	distal
436N	VDSVGGGSESRSL[D/N]DS	6	distal
429C	VDSVGG[G/C]GSESRSLDS	1	proximal

PTM Site: 434S

Affected site:

Position: 434

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
433W	GGGSES[R/W]RSLDSPTSS	1	proximal
432C	GGGSE[S/C]SRSLDSPTSS	2	proximal
431Q	GGGS[E/Q]ESRSLDSPTSS	3	distal
436N	GGGSESRSL[D/N]DSPTSS	2	network-rewiring
429C	GG[G/C]GSESRSLDSPTSS	5	distal
437A	GGGSESRSLD[S/A]SPTSS	3	network-rewiring
440F	GGGSESRSLDSPT[S/F]SS	6	distal

PTM Site: 437S

Affected site:

Position: 437

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
433W	SES[R/W]RSLDSPTSSPGA	4	distal
432C	SE[S/C]SRSLDSPTSSPGA	5	distal
431Q	S[E/Q]ESRSLDSPTSSPGA	6	distal
436N	SESRSL[D/N]DSPTSSPGA	1	proximal
437A	SESRSLD[S/A]SPTSSPGA	0	direct
440F	SESRSLDSPT[S/F]SSPGA	3	network-rewiring

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