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Mutation:
TP53 L330P
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Li-Fraumeni syndrome
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 327Y
Affected site:
Position: 327
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 333H | KKPLDGEYFTLQI[R/H]RG | 6 |
distal
|
| 333C | KKPLDGEYFTLQI[R/C]RG | 6 |
distal
|
| 332M | KKPLDGEYFTLQ[I/M]IRG | 5 |
distal
|
| 331R | KKPLDGEYFTL[Q/R]QIRG | 4 |
distal
|
| 331K | KKPLDGEYFTL[Q/K]QIRG | 4 |
distal
|
| 330P | KKPLDGEYFT[L/P]LQIRG | 3 |
distal
|
| 329I | KKPLDGEYF[T/I]TLQIRG | 2 |
proximal
|
| 329A | KKPLDGEYF[T/A]TLQIRG | 2 |
proximal
|
| 328S | KKPLDGEY[F/S]FTLQIRG | 1 |
proximal
|
| 325V | KKPLD[G/V]GEYFTLQIRG | 2 |
proximal
|
| 325E | KKPLD[G/E]GEYFTLQIRG | 2 |
proximal
|
| 325R | KKPLD[G/R]GEYFTLQIRG | 2 |
proximal
|
| 324Y | KKPL[D/Y]DGEYFTLQIRG | 3 |
network-rewiring
|
| 324H | KKPL[D/H]DGEYFTLQIRG | 3 |
network-rewiring
|
| 323P | KKP[L/P]LDGEYFTLQIRG | 4 |
distal
|
| 322S | KK[P/S]PLDGEYFTLQIRG | 5 |
distal
|
| 322T | KK[P/T]PLDGEYFTLQIRG | 5 |
distal
|
| 331H | KKPLDGEYFTL[Q/H]QIRG | 4 |
distal
|
| 332F | KKPLDGEYFTLQ[I/F]IRG | 5 |
distal
|
PTM Site: 333R
Affected site:
Position: 333
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
PTM Site: 335R
Affected site:
Position: 335
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
PTM Site: 337R
Affected site:
Position: 337
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
External references
dbSNP:
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