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Mutation:
TP53 R110P
Summary
Isoform:
Position:
110
Ref:
R
Mutation:
P
PTM impact:
direct
PTM affected:
3
Kinases:
AURKA
Clinical Information
Cancer types: (TCGA MC3)
LGG, SKCM
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 106S
Affected site:
Position: 106
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
PTM Site: 110R
Affected site:
Position: 110
Residue: R
Type: methylation
Impact:
directOther known mutations affecting this site
PTM Site: 115H
Affected site:
Position: 115
Residue: H
Type: methylation
Impact:
distalOther known mutations affecting this site
External references
dbSNP:
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