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Mutation:
TP53 F113I
Summary
Isoform:
Position:
113
Ref:
F
Mutation:
I
PTM impact:
proximal
PTM affected:
4
Kinases:
AURKA
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
Panc-AdenoCA
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 106S
Affected site:
Position: 106
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
PTM Site: 110R
Affected site:
Position: 110
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
PTM Site: 115H
Affected site:
Position: 115
Residue: H
Type: methylation
Impact:
proximalOther known mutations affecting this site
PTM Site: 120K
Affected site:
Position: 120
Residue: K
Type: ubiquitination, acetylation
Impact:
distalOther known mutations affecting this site
Mutation | In sequence | Distance | Impact |
---|---|---|---|
126C | FLHSGTAKSVTCT[Y/C]YS | 6 |
distal
|
126D | FLHSGTAKSVTCT[Y/D]YS | 6 |
distal
|
126N | FLHSGTAKSVTCT[Y/N]YS | 6 |
distal
|
125M | FLHSGTAKSVTC[T/M]TYS | 5 |
distal
|
125R | FLHSGTAKSVTC[T/R]TYS | 5 |
distal
|
125K | FLHSGTAKSVTC[T/K]TYS | 5 |
distal
|
125P | FLHSGTAKSVTC[T/P]TYS | 5 |
distal
|
124G | FLHSGTAKSVT[C/G]CTYS | 4 |
distal
|
124S | FLHSGTAKSVT[C/S]CTYS | 4 |
distal
|
123I | FLHSGTAKSV[T/I]TCTYS | 3 |
distal
|
122M | FLHSGTAKS[V/M]VTCTYS | 2 |
proximal
|
121P | FLHSGTAK[S/P]SVTCTYS | 1 |
proximal
|
120E | FLHSGTA[K/E]KSVTCTYS | 0 |
direct
|
119G | FLHSGT[A/G]AKSVTCTYS | 1 |
proximal
|
119P | FLHSGT[A/P]AKSVTCTYS | 1 |
proximal
|
118I | FLHSG[T/I]TAKSVTCTYS | 2 |
proximal
|
117V | FLHS[G/V]GTAKSVTCTYS | 3 |
distal
|
117R | FLHS[G/R]GTAKSVTCTYS | 3 |
distal
|
116A | FLH[S/A]SGTAKSVTCTYS | 4 |
distal
|
115R | FL[H/R]HSGTAKSVTCTYS | 5 |
distal
|
115N | FL[H/N]HSGTAKSVTCTYS | 5 |
distal
|
114S | F[L/S]LHSGTAKSVTCTYS | 6 |
distal
|
126H | FLHSGTAKSVTCT[Y/H]YS | 6 |
distal
|
126S | FLHSGTAKSVTCT[Y/S]YS | 6 |
distal
|
121Y | FLHSGTAK[S/Y]SVTCTYS | 1 |
proximal
|
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