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Mutation:
TP53 P278H
Summary
Isoform:
Position:
278
Ref:
P
Mutation:
H
PTM impact:
distal
PTM affected:
1
Kinases:
AURKB
Clinical Information
Cancer types: (TCGA MC3)
LUAD, LUSC, SARC, ESCA
Cancer types: (PCAWG)
Ovary-AdenoCA
Disease Annotations: (ClinVar)
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 284T
Affected site:
Position: 284
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
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Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 284I | CPGRDRR[T/I]TEEENLRK | 0 |
direct
|
| 284S | CPGRDRR[T/S]TEEENLRK | 0 |
direct
|
| 284A | CPGRDRR[T/A]TEEENLRK | 0 |
direct
|
| 284P | CPGRDRR[T/P]TEEENLRK | 0 |
direct
|
| 285V | CPGRDRRT[E/V]EEENLRK | 1 |
proximal
|
External references
dbSNP:
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